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The anterior lens capsule used as support material in RPE cell-transplantation by Jair Nicolini; Jens Folke Kiilgaard; Anne Katrine Wiencke; Steffen Heegaard; Erik Scherfig; Jan Ulrik Prause; Morten La Cour is a Medicine article available to read on EtoBox.

What is The anterior lens capsule used as support material in RPE cell-transplantation about?

## Purpose: To investigate the use of an ocular basement membrane as support material for transplanted porcine rpe cells. ## Methods: Porcine rpe cells were grown on bovine corneal extracellular matrix (ecm), isolated bovine- and porcine lens capsules, and tissue culture plastic. cell density, and cell morphology were studied by phase contrast microscopy and transmission electron microscopy. ## Results: Rpe cells grown on porcine anterior lens capsule and on ecm obtained better morphology and higher final cell density than cells grown on plastic and on bovine anterior lens capsule. it was possible to transplant the porcine anterior lens capsule to the subretinal space in pigs. within two weeks of observation, the lens capsule was well tolerated in the subretinal space. ## Conclusion: The anterior lens capsule seems to be promising as support material for use in rpe cell-transplantation.

Who reads The anterior lens capsule used as support material in RPE cell-transplantation?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Jair Nicolini; Jens Folke Kiilgaard; Anne Katrine Wiencke; Steffen Heegaard; Erik Scherfig; Jan Ulrik Prause; Morten La Cour
Publisher
John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1395-3907)
Published
2000
Language
EN
Field
Medicine (Health Sciences)

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