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A novel extrusion-based 3D bioprinting system for skeletal muscle tissue engineering by E Fornetti; F De Paolis; C Fuoco; S Bernardini; S M Giannitelli; A Rainer; D Seliktar; F Magdinier; J Baldi; R Biagini; S Cannata; S Testa; C Gargioli is a Engineering article available to read on EtoBox.
What is A novel extrusion-based 3D bioprinting system for skeletal muscle tissue engineering about?
Abstract Three-dimensional (3D) bioprinting is an emerging technology, which turned out to be an optimal tool for tissue engineering approaches. To date, different printing systems have been developed. Among them, the extrusion-based approach demonstrated to be the most suitable for skeletal muscle tissue engineering, due to its ability to produce and deposit printing fibers in a parallel pattern that well mimic the native skeletal muscle tissue architecture. In tissue bioengineering, a key role is played by biomaterials, which must possess the key requisite of ‘printability’. Nevertheless, this feature is not often well correlated with cell requirements, such as motives for cellular adhesion and/or absorbability. To overcome this hurdle, several efforts have been made to obtain an effective bioink by combining two different biomaterials in order to reach a good printability besides a suitable biological activity. However, despite being efficient, this strategy reveals several outcomes limitations. We report here the development and characterization of a novel extrusion-based 3D bioprinting system, and its application for correction of volumetric muscle loss (VML) injury in a mouse
Who reads A novel extrusion-based 3D bioprinting system for skeletal muscle tissue engineering?
It is typically read by researchers, students, and practitioners in Engineering.
- Author
- E Fornetti; F De Paolis; C Fuoco; S Bernardini; S M Giannitelli; A Rainer; D Seliktar; F Magdinier; J Baldi; R Biagini; S Cannata; S Testa; C Gargioli
- Publisher
- IOP Publishing
- Published
- 2023
- Language
- EN
- Field
- Engineering (Physical Sciences)