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Ablation Versus Laparoscopic Adrenalectomy for the Treatment of Aldosterone‐producing Adenoma: a Meta-analysis by Jin Chen; Juan Wu; Rui Zhu; Lu Lu; Xi-Juan Ma is a Medicine article available to read on EtoBox.

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## Purpose: To assess the relative clinical efficacy and safety of ablation and laparoscopic adrenalectomy (la) for the treatment of adrenal aldosterone-producing adenoma (apa). ## Materials and methods: Pubmed, embase, and cochrane library databases were searched for relevant studies, while the meta-analysis was performed with revman v5.3. ## Results: After initially identifying 496 potentially relevant studies, five were ultimately included in the final meta-analysis. in total, these studies contained 128 patients that underwent la and 91 patients that underwent ablation to treat apa. clinical success rates were comparable between these two groups (or: 0.55, p = 0.20), whereas the pooled decreases of systolic and diastolic blood pressure were significantly larger in the ablation group (p = 0.01 and 0.002, respectively). pooled changes in the aldosterone-to-renin ratio (arr), serum potassium levels, and medication use were similar in both groups (p = 0.62, 0.24, and 0.96, respectively). the average operative duration in the ablation group was somewhat shorter, but the difference was not significant (md: - 57.99; p = 0.05), whereas the average blood loss and postoperative hospital

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Author

Jin Chen; Juan Wu; Rui Zhu; Lu Lu; Xi-Juan Ma

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)