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1) Manual colorimetric methods for measuring uric acid in blood and urine rely on the chemical oxidation of uric acid and the reduction of sodium tungstate to yield a chromophore, but have many inherent difficulties including interference from other reducing substances. 2) Over 50 years, numerous modifications have been published to address issues like protein precipitation, turbidity, non-linearity, and chemical interference, but fundamental problems remain. 3) Automated colorimetric methods face similar
- Author
- musembijosef2011
- Language
- EN