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Can I read Can Colorectal Delivery Technology Provide a Platform for Enteral Oligonucleotide-based Therapeutics? on EtoBox?
Can Colorectal Delivery Technology Provide a Platform for Enteral Oligonucleotide-based Therapeutics? by Masahiro Murakami; Chie Watanabe is a Medicine article available to read on EtoBox.
What is Can Colorectal Delivery Technology Provide a Platform for Enteral Oligonucleotide-based Therapeutics? about?
Nucleic acid-based therapeutics including antisense and siRNA oligonucleotides has been expected as an innovative treatment for intractable diseases. Oral drug delivery is the most patient-friendly route of administration but developing an effective delivery system for oligonucleotides remains a major challenge. In this commentary, we discuss the potential benefits of the colorectal route as another platform for the development of oral oligonucleotide therapeutics. The importance of the targeting or the availability of oligonucleotides in targeted tissue is highlighted in contrast to systemic availability, while the liver-targeted enteral siRNA delivery technology that we recently developed is introduced.
Who reads Can Colorectal Delivery Technology Provide a Platform for Enteral Oligonucleotide-based Therapeutics??
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Masahiro Murakami; Chie Watanabe
- Publisher
- International Research and Cooperation Association for Bio & Socio-Sciences Advancement; International Advancement Center for Medicine & Health Research Co., Ltd. (IACMHR Co., Ltd.); International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA) (ISSN 1881-7831)
- Published
- 2016
- Language
- EN
- Field
- Medicine (Life Sciences)