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Olfactory Receptor Gene Expression in Tiger Salamander Olfactory Epithelium by James E. Marchand; Xinhai Yang; Dona Chikaraishi; Jurgen Krieger; Heinz Breer; John S. Kauer is a Neuroscience article available to read on EtoBox.

What is Olfactory Receptor Gene Expression in Tiger Salamander Olfactory Epithelium about?

Physiological studies of odor-elicited responses from the olfactory epithelium and bulb in the tiger salamander, Ambystoma tigrinum, have elucidated a number of features of olfactory coding that appear to be conserved across several vertebrate species. This animal model has provided an accessible in vivo system for observing individual and ensemble olfactory responses to odorant stimulation using biochemical, neurophysiological, and behavioral assays. In this paper we have complemented these studies by characterizing 35 candidate odorant receptor genes. These receptor sequences are similar to those of the large families of olfactory receptors found in mammals and fish. In situ hybridization, using RNA probes to 20 of these sequences, demonstrates differential distributions of labeled cells across the extent and within the depth of the olfactory epithelium. The distributions of cells labeled with probes to different receptors show spatially restricted patterns that are generally localized to different degrees in medial-lateral and anterior-posterior directions. The patterns of receptor expression in the ventral olfactory epithelium (OE) are mirrored in the dorsal OE. We present a hy

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It is typically read by researchers, students, and practitioners in Neuroscience.

Author
James E. Marchand; Xinhai Yang; Dona Chikaraishi; Jurgen Krieger; Heinz Breer; John S. Kauer
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0021-9967)
Published
2004
Language
EN
Field
Neuroscience (Life Sciences)

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