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Dysfunctional Vestibular System Causes a Blood Pressure Drop in Astronauts Returning from Space by Emma Hallgren; Pierre-François Migeotte; Ludmila Kornilova; Quentin Delière; Erik Fransen; Dmitrii Glukhikh; Steven T. Moore; Gilles Clément; André Diedrich; Hamish MacDougall; Floris L. Wuyts is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Dysfunctional Vestibular System Causes a Blood Pressure Drop in Astronauts Returning from Space about?

## Abstract It is a challenge for the human body to maintain stable blood pressure while standing. The body’s failure to do so can lead to dizziness or even fainting. For decades it has been postulated that the vestibular organ can prevent a drop in pressure during a position change – supposedly mediated by reflexes to the cardiovascular system. We show – for the first time – a significant correlation between decreased functionality of the vestibular otolith system and a decrease in the mean arterial pressure when a person stands up. Until now, no experiments on Earth could selectively suppress both otolith systems; astronauts returning from space are a unique group of subjects in this regard. Their otolith systems are being temporarily disturbed and at the same time they often suffer from blood pressure instability. In our study, we observed the functioning of both the otolith and the cardiovascular system of the astronauts before and after spaceflight. Our finding indicates that an intact otolith system plays an important role in preventing blood pressure instability during orthostatic challenges. Our finding not only has important implications for human space exploration; they m

Who reads Dysfunctional Vestibular System Causes a Blood Pressure Drop in Astronauts Returning from Space?

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
Emma Hallgren; Pierre-François Migeotte; Ludmila Kornilova; Quentin Delière; Erik Fransen; Dmitrii Glukhikh; Steven T. Moore; Gilles Clément; André Diedrich; Hamish MacDougall; Floris L. Wuyts
Publisher
Springer Science and Business Media LLC
Published
2015
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)

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