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1. The survey model Sequential ~[ultiple At, toAnalyzer (S~IA-12/30) was modified for the purpose of conducting routine analyses of laboratory and domestic animal serums. 2. Phosphorus concentrations, as well as lactic dehydrogenase and alkaline phosphatase activities, which are much greater than levels found in hnnlan serum, necessitated changes in methods used. 3. Creatinine analysis was substituted for albumin, and chloride substituted for uric acid. INVESTIGATIONS RELATIVE TO AGING AND CHRONIC DISEASES IN ANIMALS necessitated reproducible laboratory procedures that could be employed througlaout longitudinal studies. There are nunlerous reports concerned with the use of the multiple analy,sis system for screening samples; however, few investigators have discussed the capabilities of the survey model Sequential 3lultiple Auto-Analyzer\* ($3IA-12/30) for research. The S,~1A-12/30 was modified to meet the requirements of longitudinal, multispecies research projects. . ## ~[ATERIALS AND .'~IE'I'HODS The basic instrument which was modified was the survey model $31A-12/30 (1, 2). The flow diagram of the modified instrument is shown in Fig. 1. ## Chloride .4 n. lysis: Since the $31A-12

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Author

M.E. Tumbleson

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0009-9120)

Published

1968

Language

EN

Field

Medicine (Health Sciences)