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Drying Induced Hydrophobic Polymer Collapse by Wolde, Pieter Rein ten; Chandler, David is a scholarly article available to read on EtoBox.

What is Drying Induced Hydrophobic Polymer Collapse about?

We have used computer simulation to study the collapse of a hydrophobic chain in water. We find that the mechanism of collapse is much like that of a first order phase transition. The evaporation of water in the vicinity of the polymer provides the driving force for collapse, and the rate limiting step is the nucleation of a sufficiently large vapor bubble. The study is made possible through the application of transition path sampling and a coarse grained treatment of liquid water. Relevance of our findings to understanding the folding and assembly of proteins is discussed.

Author

Wolde, Pieter Rein ten; Chandler, David

Published

2002

Language

EN