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The OPTIMISE II trial evaluated the effectiveness and safety of cardiac output-guided haemodynamic therapy in 2498 patients undergoing major gastrointestinal surgery. The study found no significant reduction in postoperative infections compared to usual care, and the intervention was associated with an increased incidence of acute cardiac events, particularly arrhythmias. Consequently, routine use of this treatment approach in unselected patients is not recommended.

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dockanje

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EN