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Can I read In situ hybridization analysis of substance P receptor in the rat retina on EtoBox?
In situ hybridization analysis of substance P receptor in the rat retina by Akitoshi Kondoh; Takeshi Houtani; Teizo Ueyama; Kazuyasu Baba; Michiko Ikeda; Kazuya Yamagishi; Hirohiko Miki; Masanobu Uyama; Shigetada Nakanishi; Tetsuo Sugimoto is a Neuroscience article available to read on EtoBox.
What is In situ hybridization analysis of substance P receptor in the rat retina about?
Substance P receptor is known to provide a principal interface between tachykinin peptides and tachykinin-sensitive cells in retinal circuitry and to produce several physiological functions such as excitation of ganglion cells. We reported results of in situ hybridization analysis of substance P receptor in rat retina using digoxigenin-labeled RNA probes to yield discrete cell labeling. Distinct hybridization signal was present in a great majority of ganglion cells that provide retinal fibers to a central target. It was also present in a subpopulation of amacrine cells. Following optic nerve crush, ganglion cells lost their hybridization signal in a time-dependent manner, while hybridization-positive amacrine cells were persistently seen. From the results, we identified the hybridization message as distinctly localized to two systems, output cells and intrinsic cells in retinal circuitry.
Who reads In situ hybridization analysis of substance P receptor in the rat retina?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Akitoshi Kondoh; Takeshi Houtani; Teizo Ueyama; Kazuyasu Baba; Michiko Ikeda; Kazuya Yamagishi; Hirohiko Miki; Masanobu Uyama; Shigetada Nakanishi; Tetsuo Sugimoto
- Publisher
- Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0014-4819)
- Published
- 1996
- Language
- EN
- Field
- Neuroscience (Life Sciences)