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What is Subacute Dermal Toxicity Testing Guide about?

This document provides guidelines for a 21/28-day repeated dose dermal toxicity study. Key points include: - Animals such as rats, rabbits, or guinea pigs are exposed to graduated doses of a test substance daily via the skin for 21 or 28 days. - Multiple dose levels are used including a control, with the highest dose expected to produce toxic effects and the lowest not producing any toxicity. - Animals are observed daily for signs of toxicity and weighed weekly. After the study period, surviving animal

Author

liliana pinto

Language

EN