Can I read Infection with GB virus C (GBV-C) in patients with chronic liver disease or on maintenance hemodialysis in Indonesia on EtoBox?

Infection with GB virus C (GBV-C) in patients with chronic liver disease or on maintenance hemodialysis in Indonesia by Tsuda, Fumio; Hadiwandowo, Soeliadi; Sawada, Naoto; Fukuda, Masako; Tanaka, Takeshi; Okamoto, Hiroaki; Miyakawa, Yuzo; Mayumi, Makoto is a Medicine article available to read on EtoBox.

What is Infection with GB virus C (GBV-C) in patients with chronic liver disease or on maintenance hemodialysis in Indonesia about?

RNA of a non-A to E hepatitis virus identified recently and designated provisionally GB virus C (GBV-C), was sought in patients in Indonesia by reverse-transcription polymerase chain reaction with nested primers deduced from a helicaselike region. GBV-C RNA was detected in 32 (55%) of 58 patients on maintenance hemodialysis at a frequency significantly higher ( P < 0.001) than that in seven (5%) of 149 patients with chronic liver disease. Co-infection with hepatitis C virus was observed in 26 (81%) of the 32 patients on hemodialysis and in five (71%) of the seven patients with liver disease who were infected with GBV-C. Complete identity was observed in a sequence of 100 base pairs in the helicase-like region for GBV-C cDNA clones from some patients on maintenance hemodialysis. These results indicate that the patients on hemodialysis would be at high risk for GBV-C infection, which would be transmitted by transfusion and patient-to-patient routes.

Who reads Infection with GB virus C (GBV-C) in patients with chronic liver disease or on maintenance hemodialysis in Indonesia?

Author

Tsuda, Fumio; Hadiwandowo, Soeliadi; Sawada, Naoto; Fukuda, Masako; Tanaka, Takeshi; Okamoto, Hiroaki; Miyakawa, Yuzo; Mayumi, Makoto

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0146-6615)

Published

1996

Language

EN

Field

Medicine (Health Sciences)