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3D biosensors in advanced medical diagnostics of high mortality diseases by Rita Rebelo; Ana I. Barbosa; David Caballero; Il Keun Kwon; Joaquim M. Oliveira; Subhas C. Kundu; Rui L. Reis; Vitor M. Correlo is a Engineering article available to read on EtoBox.

What is 3D biosensors in advanced medical diagnostics of high mortality diseases about?

Cardiovascular diseases, cancer, and diabetes are high mortality diseases, which account for almost two thirds of all deaths worldwide. Their early detection and continuous evaluation are fundamental for an improved patient prognosis and reduced socioeconomic impact. Current biosensor technologies are typically based on the analysis of whole blood samples from patients for the detection of disease-specific biomarkers. However, these technologies display serious shortcomings, such as reduced sensitivity and dynamic range, limited in vivo applicability, and lack of continuous monitoring. There is the urgent need for new diagnostic and treatment follow-up tools, which allow for the early detection of the pathology as well as for the continuous monitoring of the physiological responses to specific therapies. During the last years, a new generation of biosensor technologies with improved performance has emerged in the biomedical sector. The combination of advanced biomaterial methods, biochemical tools, and micro/nanotechnology approaches has resulted in the development of innovative three-dimensional (3D) biosensor platforms for advanced medical diagnosis. In this review, we report th

Who reads 3D biosensors in advanced medical diagnostics of high mortality diseases?

Author

Rita Rebelo; Ana I. Barbosa; David Caballero; Il Keun Kwon; Joaquim M. Oliveira; Subhas C. Kundu; Rui L. Reis; Vitor M. Correlo

Publisher

Elsevier BV

Published

2019

Language

EN

Field

Engineering (Physical Sciences)