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Medication-related osteonecrosis of the jaw (MRONJ) involves necrosis or death of the jaw bone associated with antiresorptive or anti-angiogenic therapies. Antiresorptive medications like bisphosphonates inhibit osteoclastic activity and bone resorption, reducing bone turnover rates. Prolonged use can lead to over-mineralization of bone and sclerotic changes in the jaw.
- Author
- napat kidsanakaraket
- Language
- EN