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Infertility, Recurrent Pregnancy Loss, and Risk of Stroke: Pooled Analysis of Individual Patient Data of 618 851 Women by Chen Liang; Hsin-Fang Chung; Annette J Dobson; Kunihiko Hayashi; Yvonne T van der Schouw; Diana Kuh; Rebecca Hardy; Carol A Derby; Samar R El Khoudary; Imke Janssen; Sven Sandin; Elisabete Weiderpass; Gita D Mishra is a Health Professions article available to read on EtoBox.
What is Infertility, Recurrent Pregnancy Loss, and Risk of Stroke: Pooled Analysis of Individual Patient Data of 618 851 Women about?
## Abstract ## Objective To examine the associations of infertility, recurrent miscarriage, and stillbirth with the risk of first non-fatal and fatal stroke, further stratified by stroke subtypes. ## Design Individual participant pooled analysis of eight prospective cohort studies. ## Setting Cohort studies across seven countries (Australia, China, Japan, Netherlands, Sweden, the United Kingdom, and the United States) participating in the InterLACE (International Collaboration for a Life Course Approach to Reproductive Health and Chronic Disease Events) consortium, which was established in June 2012. ## Participants 618 851 women aged 32.0-73.0 years at baseline with data on infertility, miscarriage, or stillbirth, at least one outcome event (non-fatal or fatal stroke), and information on covariates were included; 93 119 women were excluded. Of the participants, 275 863 had data on non-fatal and fatal stroke, 54 716 only had data on non-fatal stroke, and 288 272 only had data on fatal stroke. ## Main outcome and measures Non-fatal strokes were identified through self-reported questionnaires, linked hospital data, or national patient registers. Fatal strokes were identified through
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- Author
- Chen Liang; Hsin-Fang Chung; Annette J Dobson; Kunihiko Hayashi; Yvonne T van der Schouw; Diana Kuh; Rebecca Hardy; Carol A Derby; Samar R El Khoudary; Imke Janssen; Sven Sandin; Elisabete Weiderpass; Gita D Mishra
- Publisher
- BMJ
- Published
- 2022
- Language
- EN
- Field
- Health Professions (Health Sciences)