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Can I read Effects of Short-term Exposures to Ultrafine Particles Near an Airport in Healthy Subjects on EtoBox?
Effects of Short-term Exposures to Ultrafine Particles Near an Airport in Healthy Subjects by A. Lammers; N.A.H. Janssen; A.J.F. Boere; M. Berger; C. Longo; S.J.H. Vijverberg; A.H. Neerincx; A.H. Maitland - van der Zee; F.R. Cassee is a Environmental Science article available to read on EtoBox.
What is Effects of Short-term Exposures to Ultrafine Particles Near an Airport in Healthy Subjects about?
Background: Recent studies reported elevated concentrations of ultrafine particles (UFP) near airports. Little is known about the health effects of UFP from aviation. Since UFP can deposit deep into the lungs and other organs, they may cause significant adverse health effects. Objective: We investigated health effects of controlled short-term human exposure to UFP near a major airport. Methods: In this study, 21 healthy non-smoking volunteers (age range: 18-35 years) were repeatedly (2-5 visits) exposed for 5 h to ambient air near Schiphol Airport, while performing intermittent moderate exercise (i.e. cycling). Pre-to post-exposure changes in cardiopulmonary outcomes (spirometry, forced exhaled nitric oxide, electrocardiography and blood pressure) were assessed and related to total-and size-specific particle number concentrations (PNC), using linear mixed effect models. Results: The PNC was on average 53,500 particles/cm 3 (range 10,500-173,200). A 5-95th percentile increase in exposure to UFP (i.e. 125,400 particles/cm 3 ) was associated with a decrease in FVC of -73.8 mL (95% CI -138.8 --0.4) and a prolongation of the corrected QT (QTc) interval by 9.9 ms (95% CI 2.0 -19.1). Thes
Who reads Effects of Short-term Exposures to Ultrafine Particles Near an Airport in Healthy Subjects?
It is typically read by researchers, students, and practitioners in Environmental Science.
- Author
- A. Lammers; N.A.H. Janssen; A.J.F. Boere; M. Berger; C. Longo; S.J.H. Vijverberg; A.H. Neerincx; A.H. Maitland - van der Zee; F.R. Cassee
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0160-4120)
- Published
- 2020
- Language
- EN
- Field
- Environmental Science (Physical Sciences)