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Granulomatous inflammation is a chronic inflammatory response marked by activated macrophages and multinucleated giant cells, often caused by infections like tuberculosis and non-infectious conditions like sarcoidosis. The process involves persistent antigens activating T lymphocytes, leading to macrophage activation and granuloma formation. The Ghon complex, associated with primary pulmonary tuberculosis, includes a subpleural lung lesion, involved lymphatics, and enlarged hilar lymph nodes, with healing r
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