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EUS-guided gastroenterostomy for management of malignant gastric outlet obstruction: a prospective cohort study with matched comparison with enteral stenting by Giuseppe Vanella; Giuseppe Dell’Anna; Gabriele Capurso; Patrick Maisonneuve; Michiel Bronswijk; Stefano Crippa; Domenico Tamburrino; Marina Macchini; Giulia Orsi; Andrea Casadei-Gardini; Luca Aldrighetti; Michele Reni; Massimo Falconi; Schalk van der Merwe; Paolo Giorgio Arcidiacono is a Medicine article available to read on EtoBox.

What is EUS-guided gastroenterostomy for management of malignant gastric outlet obstruction: a prospective cohort study with matched comparison with enteral stenting about?

Background and Aims: Retrospective studies on malignant gastric outlet obstruction (mGOO) highlighted several advantages of EUS-guided gastroenterostomy (EUS-GE) over enteral stenting (ES). However, no prospective evidence is available. The aim of this study was to report on clinical outcomes of EUS-GE in a prospective cohort study, with a subgroup comparison versus ES. Methods: All consecutive patients endoscopically treated for mGOO between December 2020 and December 2022 in a tertiary, academic center were enrolled in a prospective registry (Prospective Registry of Therapeutic Endoscopic Ultrasound [PROTECT]; NCT04813055) and followed up every 30 days to register efficacy/safety outcomes. EUS-GE and ES cohorts were matched according to baseline frailty and oncologic disease. Results: A total of 104 patients were treated for mGOO during the study; 70 (58.6% male subjects; median age, 64 [interquartile range, 58-73] years; 75.7% pancreatic cancer, 60.0% metastatic cancer) underwent EUS-GE via the wireless simplified technique. Technical success was 97.1% and clinical success was 97.1% after a median of 1.5 (interquartile range, 1-2) days. Adverse events occurred in 9 (12.9%) patie

Who reads EUS-guided gastroenterostomy for management of malignant gastric outlet obstruction: a prospective cohort study with matched comparison with enteral stenting?

Author

Giuseppe Vanella; Giuseppe Dell’Anna; Gabriele Capurso; Patrick Maisonneuve; Michiel Bronswijk; Stefano Crippa; Domenico Tamburrino; Marina Macchini; Giulia Orsi; Andrea Casadei-Gardini; Luca Aldrighetti; Michele Reni; Massimo Falconi; Schalk van der Merwe; Paolo Giorgio Arcidiacono

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Health Sciences)