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What is Spectrophotometric Assay of Sulfadiazine about?

A new spectrophotometric method for the assay of sulfadiazine (SDZ) drug was developed, utilizing a diazotization reaction with 4-amino-2-hydroxy acetophenon to form a colored complex measured at 410 nm. The method demonstrated high sensitivity with a limit of detection of 0.443 µg mL-1 and was effective for both pure SDZ and various pharmaceutical preparations. The procedure is rapid, simple, and does not require solvent extraction, making it suitable for trace analysis of SDZ in commercial products.

Author

DEEPTHI M N

Language

EN