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What is HPLC Method for Adapalene Gel Analysis about?

This document describes the development and validation of a simple HPLC-DAD method for the determination of adapalene in topical gel formulations. Key points: 1) An isocratic HPLC method using a C8 column and mobile phase of acetonitrile-water was developed and validated for the analysis of adapalene in raw materials and gel formulations. 2) The method was specific, linear, precise, accurate, robust, and stability-indicating as required by ICH guidelines. 3) Forced degradation studies showed the method

Author

Abdelrhman Abooda

Language

EN