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This randomized controlled trial tested the effectiveness of Therabot, a generative AI chatbot, for treating mental health symptoms in adults with major depressive disorder, generalized anxiety disorder, or high-risk feeding and eating disorders. Results indicated significant reductions in symptoms for Therabot users compared to a waitlist control, with high user engagement and positive ratings of the therapeutic alliance. This study is the first to demonstrate the potential of a fully generative AI therapy

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