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Review of Thymic Hormones in Cancer Diagnosis and Treatment by Bela Bodey; Bela Bodey Jr; Stuart E Siegel; Hans E Kaiser is a Immunology and Microbiology article available to read on EtoBox.

What is Review of Thymic Hormones in Cancer Diagnosis and Treatment about?

The thymus is an endocrine organ. A uni®ed, physiological concept of humoral regulations of the immune response has emerged in the last three decades. The thymus is the major site of production of immunocompetent T lymphocytes from their hematopoietic stem cells. This complex process required direct cell to cell, receptor based interactions, as well as in situ paracrine information via the numerous cytokines and thymic hormones produced by the cells of thymic microenvironment. Thymic hormones induce in situ T-cell marker dierentiation, expression and functions. These polypeptide hormones have also been shown by means of immunocytochemistry to localize in the reticulo-epithelial (RE) cells of the thymic cellular microenvironment. Due to the great complexity of the intrathymic maturation sequence of T lymphocytes and the diverse immunophenotypically unique subpopulations of T lymphocytes, it is quite unlikely that a single thymic humoral factor could control all of the molecular steps and cell populations involved. It is much more likely that an extremely rich and diverse, but genetically determined, milieu is present within the thymus, and that thus the control of intrathymic T lymp

Who reads Review of Thymic Hormones in Cancer Diagnosis and Treatment?

Author

Bela Bodey; Bela Bodey Jr; Stuart E Siegel; Hans E Kaiser

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0192-0561)

Published

2000

Language

EN

Field

Immunology and Microbiology (Life Sciences)