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Asymptotic Stability for a Free Boundary Tumor Model with Angiogenesis by Huang, Yaodan; Zhang, Zhengce; Hu, Bei is a scholarly article available to read on EtoBox.

What is Asymptotic Stability for a Free Boundary Tumor Model with Angiogenesis about?

In this paper, we study a free boundary problem modeling solid tumor growth with vasculature which supplies nutrients to the tumor; this is characterized in the Robin boundary condition. It was recently established [Discrete Cont. Dyn. Syst. 39 (2019) 2473-2510] that for this model, there exists a threshold value $\mu^\ast$ such that the unique radially symmetric stationary solution is linearly stable under non-radial perturbations for $0<\mu<\mu^\ast$ and linearly unstable for $\mu>\mu^\ast$. In this paper we further study the nonlinear stability of the radially symmetric stationary solution, which introduces a significant mathematical difficulty: the center of the limiting sphere is not known in advance owing to the perturbation of mode 1 terms. We prove a new fixed point theorem to solve this problem, and finally obtain that the radially symmetric stationary solution is nonlinearly stable for $0<\mu<\mu^\ast$ when neglecting translations.

Author

Huang, Yaodan; Zhang, Zhengce; Hu, Bei

Published

2020

Language

EN