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Prophylactic EUS-guided gallbladder drainage prevents acute cholecystitis in patients with malignant biliary obstruction and cystic duct orifice involvement: a randomized trial (with video) by Carlos Robles-Medranda; Roberto Oleas; Miguel Puga-Tejada; Juan Alcivar-Vasquez; Raquel Del Valle; Juan Olmos; Martha Arevalo-Mora; Maria Egas-Izquierdo; Daniela Tabacelia; Jorge Baquerizo-Burgos; Hannah Pitanga-Lukashok is a Medicine article available to read on EtoBox.

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Background and aims: Patients with distal malignant biliary obstruction (MBO) and cystic duct orifice tumoral involvement have an increased risk for the development of acute cholecystitis after self-expandable metallic stent (SEMS) placement. We aimed to determine whether primary EUS-guided gallbladder drainage prevents acute cholecystitis in these patients. Methods: This was a single-center, randomized control trial in patients with distal MBO enrolled from July 2018 to July 2020. Patients were randomized into 2 groups: an interventional group treated with conventional ERCP biliary drainage with SEMS placement and subsequent primary EUS-guided gallbladder drainage (EUS-GBD) and a control group treated with conventional biliary drainage alone. The primary outcome of the study was the occurrence of post-treatment acute cholecystitis, assessed for 12 months or until death. The secondary outcomes were hospitalization length and median survival time. Results: Forty-four patients were included in the study: 22 in each group. Five patients in the control group (22.7%) and none in the intervention group experienced acute cholecystitis. The median hospitalization time was significantly low

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Author

Carlos Robles-Medranda; Roberto Oleas; Miguel Puga-Tejada; Juan Alcivar-Vasquez; Raquel Del Valle; Juan Olmos; Martha Arevalo-Mora; Maria Egas-Izquierdo; Daniela Tabacelia; Jorge Baquerizo-Burgos; Hannah Pitanga-Lukashok

Publisher

Elsevier BV

Published

2022

Language

EN

Field

Medicine (Health Sciences)