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Can I read A New Cleavage Strategy for the Solid-phase Synthesis of Secondary Amines on EtoBox?
A New Cleavage Strategy for the Solid-phase Synthesis of Secondary Amines by Paolo Conti; Dennis Demont; Jos Cals; Harry C.J. Ottenheijm; Dirk Leysen is a Chemistry article available to read on EtoBox.
What is A New Cleavage Strategy for the Solid-phase Synthesis of Secondary Amines about?
The clean and efficient cleavage of N-benzyl linked tertiary amines from a solid support (e.g. 4) by treatment with ct-chloroethyl chloroformate (ACE-CI) / methanol to yield secondary amines 7 is described. This allows the solid-phase synthetic transformation of the secondary amine 2 into 7. When the Merrifleld resin l is used the N-tethered amine-polymeric matrix ensemble is stable towards a wide variety of reaction conditions.
Who reads A New Cleavage Strategy for the Solid-phase Synthesis of Secondary Amines?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Paolo Conti; Dennis Demont; Jos Cals; Harry C.J. Ottenheijm; Dirk Leysen
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4039)
- Published
- 1997
- Language
- EN
- Field
- Chemistry (Physical Sciences)
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