Opening book details…
Can I read Characterization of serum antibody to Actinobacillus actinomycetemcomitans GroEL‐like protein in periodontitis patients and healthy subjects on EtoBox?
Characterization of serum antibody to Actinobacillus actinomycetemcomitans GroEL‐like protein in periodontitis patients and healthy subjects by K. Tabeta; H. Yoshie; K. Yamazaki is a Dentistry article available to read on EtoBox.
What is Characterization of serum antibody to Actinobacillus actinomycetemcomitans GroEL‐like protein in periodontitis patients and healthy subjects about?
Recent evidence suggests that molecular mimicry between bacterial and human heat shock protein 60 (hsp60) is involved in various conditions of autoimmune and infectious diseases. Many periodontopathic bacteria have been reported to express GroEL‐like protein that is homologous to human hsp60. In this study, the presence of antibodies to the hsp60 of __Actinobacillus actinomycetemcomitans__ in the sera of periodontitis patients and periodontally healthy control subjects was evaluated by enzyme‐linked immunosorbent assay using a recombinant __A. actinomycetemcomitans__ GroEL as an antigen. Furthermore, their cross‐reactivity with __Escherichia coli__ GroEL and __Mycobacterium bovis__ BCG hsp65 was examined. The mean values of antibody were 0.624 (range 0.088–1.113) and 0.728 (range 0.217–1.296) in control subjects and periodontitis patients, respectively. The antibody levels to __A. actinomycetemcomitans__ after absorption with __E. coli__ GroEL and __M. bovis__ BCG clearly decreased in both control subjects and periodontitis patients. The remaining antibody levels to __A. actinomycetemcomitans__ GroEL after absorption with __M. bovis__ BCG hsp65 were higher than those with __E. coli
Who reads Characterization of serum antibody to Actinobacillus actinomycetemcomitans GroEL‐like protein in periodontitis patients and healthy subjects?
It is typically read by researchers, students, and practitioners in Dentistry.
- Author
- K. Tabeta; H. Yoshie; K. Yamazaki
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0902-0055)
- Published
- 2001
- Language
- EN
- Field
- Dentistry (Health Sciences)