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Phasing of muscle gene expression with fasting-induced recovery growth in Atlantic salmon by Neil I Bower; Richard G Taylor; Ian A Johnston is a Environmental Science article available to read on EtoBox.

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## Abstract ## Background Many fish species experience long periods of fasting in nature often associated with seasonal reductions in water temperature and prey availability or spawning migrations. During periods of nutrient restriction, changes in metabolism occur to provide cellular energy via catabolic processes. Muscle is particularly affected by prolonged fasting as myofibrillar proteins act as a major energy source. To investigate the mechanisms of metabolic reorganisation with fasting and refeeding in a saltwater stage of Atlantic salmon (__Salmo salar L__.) we analysed the expression of genes involved in myogenesis, growth signalling, lipid biosynthesis and myofibrillar protein degradation and synthesis pathways using qPCR. ## Results Hierarchical clustering of gene expression data revealed three clusters. The first cluster comprised genes involved in lipid metabolism and triacylglycerol synthesis (__ALDOB__, __DGAT1__ and __LPL__) which had peak expression 3-14d after refeeding. The second cluster comprised __ADIPOQ__, __MLC2__, __IGF-I__ and __TALDO1__, with peak expression 14-32d after refeeding. Cluster III contained genes strongly down regulated as an initial response

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Author
Neil I Bower; Richard G Taylor; Ian A Johnston
Publisher
BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central, 2004-; Springer Science and Business Media LLC (ISSN 1742-9994)
Published
2009
Language
EN
Field
Environmental Science (Life Sciences)

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