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Peripheral T-cell lymphoma in childhood: A report of five cases in Taiwan by Kai-Hsin Lin; Ih-Jen Su; Rong-Long Chen; Dong-Tsamn Lin; Hwei-Fang Tien; Bo-Wen Chen; Kuo-Sin Lin is a Medicine article available to read on EtoBox.

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## Abstract We encountered five children with peripheral T‐cell lymphoma (PTL) at National Taiwan University Hospital (NTUH) from 1985–1989. The patients were four boys and one girl, aged between 5 and 13 years. The duration of prediagnostic symptoms varied from 1 month to 5 years. All had pyrexia and lymphadenopathy; one had a prolonged history of granulomatosis with repeated infection. Four had hepatosplenomegaly. One patient presented with diffuse pulmonary infiltration and impending respiratory failure. All patients were negative for human T‐cell leukemia virus (HTLV)‐I antibody, and positive for HBsAg. Four patients who had EBV‐viral capsid antigen (VCA) IgG and who were IgM tested were positive for EBV‐VCA IgG, but only two had evidence of active EBV infection. Tumor cell markers were examined and showed the following phenotypes: all patients were CD2, CD3, and CD7 positive but CD19 and CD20 negative; three patients were CD4 positive and CD8 negative; the other two patients were CD4 negative and CD8 positive. Four patients died 2–7 months after diagnosis. The remaining patient received allogeneic bone marrow transplantation and has survived free of disease for more than 22 mo

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Author

Kai-Hsin Lin; Ih-Jen Su; Rong-Long Chen; Dong-Tsamn Lin; Hwei-Fang Tien; Bo-Wen Chen; Kuo-Sin Lin

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0098-1532)

Published

1994

Language

EN

Field

Medicine (Health Sciences)