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Can I read The Evolution of Pituitary Cysts in Growth Hormone-treated Children on EtoBox?

The Evolution of Pituitary Cysts in Growth Hormone-treated Children by Matthew D. Krasnow; Nicholas A. Krasnow; Liam McGuirk; Tara P. Patale; Sarah Manely; Emily Sayegh; Benjamin Epstein; Sarriyah A. Hanif; Shilpa Mehta; Michael Tenner; Javin Schefflein; Hasit Mehta; Richard A. Noto is a Medicine article available to read on EtoBox.

What is The Evolution of Pituitary Cysts in Growth Hormone-treated Children about?

Objectives: We have previously shown that pituitary cysts may affect growth hormone secretion. This study sought to determine cyst evolution during growth hormone treatment in children. Methods: Forty-nine patients with short stature, a pituitary cyst, and at least two brain MRI scans were included. The percent of the pituitary gland occupied by the cyst (POGO) was calculated, and a cyst with a POGO of ≤15% was considered small, while a POGO >15% was considered large. Results: Thirty-five cysts were small, and 14 were large. Five of the 35 small cysts grew into large cysts, while 6 of the 14 large cysts shrunk into small cysts. Of 4 cysts that fluctuated between large and small, 3 presented as large and 1 as small. Small cysts experienced greater change in cyst volume (CV) (mean=61.5%) than large cysts (mean=-0.4%). However, large cysts had a greater net change in CV (mean=44.2 mm 3 ) than small cysts (mean=21.0 mm 3 ). Older patients had significantly larger mean pituitary volume than younger patients (435.4 mm 3 vs. 317.9 mm 3 ) and significantly larger mean CV than younger patients (77.4 mm 3 vs. 45.2 mm 3 ), but there was no significant difference in POGO between groups. Conclu

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Author
Matthew D. Krasnow; Nicholas A. Krasnow; Liam McGuirk; Tara P. Patale; Sarah Manely; Emily Sayegh; Benjamin Epstein; Sarriyah A. Hanif; Shilpa Mehta; Michael Tenner; Javin Schefflein; Hasit Mehta; Richard A. Noto
Publisher
Walter de Gruyter GmbH
Published
2022
Language
EN
Field
Medicine (Health Sciences)

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