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Can I read Severe infections caused by difficult-to-treat Gram-negative bacteria on EtoBox?
Severe infections caused by difficult-to-treat Gram-negative bacteria by Silvia Dettori; Federica Portunato; Antonio Vena; Daniele Roberto Giacobbe; Matteo Bassetti is a Medicine article available to read on EtoBox.
What is Severe infections caused by difficult-to-treat Gram-negative bacteria about?
## Purpose of review Antimicrobial resistance (AMR) in Gram-negative bacteria (GNB) poses a significant global health concern, contributing to increased infections, mortality rates, and healthcare costs. This review discusses the main clinical manifestations, therapeutic options, and recent findings in managing antibiotic-resistant GNB, with a focus on difficult-to-treat infections. ## Recent findings Difficult-to-treat resistance (DTR) is a novel classification that identifies GNB exhibiting intermediate or resistant phenotypes to first-line agents in the carbapenem, beta-lactam, and fluoroquinolone categories. The main pathogens implicated in severe infections include DTR Enterobacterales, DTR __Pseudomonas aeruginosa__, and DTR __Acinetobacter baumannii.__ Although the clinical implications of DTR strains are still under investigation, certain studies have linked them to prolonged hospital stays and poor patient outcomes. ## Summary Severe infections caused by DTR-GNB pose a formidable challenge for healthcare providers and represent a growing global health issue. The proper administration and optimization of novel antibiotics at our disposal are of paramount importance for comb
Who reads Severe infections caused by difficult-to-treat Gram-negative bacteria?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Silvia Dettori; Federica Portunato; Antonio Vena; Daniele Roberto Giacobbe; Matteo Bassetti
- Publisher
- Lippincott Williams & Wilkins
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)