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What is Bixin about?
This document summarizes a study that investigated the effects of the carotenoid bixin on cisplatin-induced oxidative stress in rats. The study found that pretreatment with bixin significantly reduced cisplatin-induced chromosome aberrations and lipid peroxidation in rats. Bixin also inhibited renal glutathione depletion caused by cisplatin. Since bixin pretreatment alone was found to be safe, the results suggest that bixin may have potential clinical application in reducing side effects of cisplatin chemot
- Author
- Aecio Vasconcelos
- Language
- EN