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Relationship Between the Overall Survival in Glioblastomas and the Radiomic Features of Intraoperative Ultrasound: a Feasibility Study by Santiago Cepeda; Sergio García-García; Ignacio Arrese; María Velasco-Casares; Rosario Sarabia is a Medicine article available to read on EtoBox.
What is Relationship Between the Overall Survival in Glioblastomas and the Radiomic Features of Intraoperative Ultrasound: a Feasibility Study about?
## Purpose: Predicting the survival of patients diagnosed with glioblastoma (gbm) is essential to guide surgical strategy and subsequent adjuvant therapies. intraoperative ultrasound (ious) can contain biological information that could be correlated with overall survival (os). we propose a simple extraction method and radiomic feature analysis based on ious imaging to estimate os in gbm patients. ## Methods: A retrospective study of surgically treated glioblastomas between march 2018 and november 2019 was performed. patients with ious b-mode and strain elastography were included. after preprocessing, segmentation and extraction of radiomic features were performed with lifex software. an evaluation of semantic segmentation was carried out using the dice similarity coefficient (dsc). using univariate correlations, radiomic features associated with os were selected. subsequently, survival analysis was conducted using cox univariate regression and kaplan-meier curves. ## Results: Sixteen patients were available for analysis. the dsc revealed excellent agreement for the segmentation of the tumour region. of the 52 radiomic features, two texture features from b-mode (conventional mean an
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- Author
- Santiago Cepeda; Sergio García-García; Ignacio Arrese; María Velasco-Casares; Rosario Sarabia
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)