Opening book details…
Can I read Enhancing Tools in Lateral Flow Assay for Improving Detection Limit and Working Range on EtoBox?
Enhancing Tools in Lateral Flow Assay for Improving Detection Limit and Working Range by N A Taranova; A V Zherdev; B B Dzantiev is a Physics and Astronomy article available to read on EtoBox.
What is Enhancing Tools in Lateral Flow Assay for Improving Detection Limit and Working Range about?
## Abstract This work is directed to the estimation of the analytical parameters for improved immunochromatographic tests. A combination of 2 approaches has been proposed to decrease the detection limit of troponin T, a biomarker of acute myocardial infarction. The first approach consists of replacing spherical gold nanoparticles, which are common markers in immunochromatography, with alternative markers, such as gold nanoflowers (AuNFs). The second approach consists of the formation of large aggregates in the analytical zone from AuNFs due to the biotin–streptavidininteraction. The improved tests demonstrated a 10-fold lowering of the detection limit (1.2 ng/ml instead of 11.1 ng/ml) and a 3-fold expanding of the working range of the determined concentrations.
Who reads Enhancing Tools in Lateral Flow Assay for Improving Detection Limit and Working Range?
It is typically read by researchers, students, and practitioners in Physics and Astronomy.
- Author
- N A Taranova; A V Zherdev; B B Dzantiev
- Publisher
- IOP Publishing
- Published
- 2021
- Language
- EN
- Field
- Physics and Astronomy (Physical Sciences)