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Can I read Histological and Biochemical Evaluation of Perichondrial Transplants in Human Articular Cartilage Defects on EtoBox?
Histological and Biochemical Evaluation of Perichondrial Transplants in Human Articular Cartilage Defects by Phianne Bouwmeester; Roel Kuijer; Els Terwindt‐Rouwenhorst; Ton van der Linden; Sjoerd Bulstra is a Medicine article available to read on EtoBox.
What is Histological and Biochemical Evaluation of Perichondrial Transplants in Human Articular Cartilage Defects about?
## Abstract From 1986 to 1992, 88 patients with articular defects in the knee were treated with a perichondrial arthroplasty. In this study, we report on the results for 22 biopsies of grafted tissue with a mean follow‐up of 21 months. Biopsies were obtained at routine arthroscopy after approximately 1 year or at arthroscopy or arthrotomy at a later stage when patients were operated on again because of recurrent complaints. Biopsies were taken only when a partial failure was present or when there was a clear failure resulting in fibrocartilage, a loose flap, or a loose body. The biopsies were analyzed histologically, biochemically for the amount of type‐II collagen, and immunohistochemically with antibodies for types I, II, and X collagen. The well‐being of the patients was investigated with use of the Hospital for Special Surgery knee score. The biopsies from 6 patients contained more than 50% hyaline cartilage. At arthroscopy, the mean relative amount of type‐II collagen was 56% in the biopsies classified as good. The cartilage of the grafted area was macroscopically normal for eight of the 22 biopsies. Histological and biochemical analysis of biopsies from failed transplants sho
Who reads Histological and Biochemical Evaluation of Perichondrial Transplants in Human Articular Cartilage Defects?
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- Author
- Phianne Bouwmeester; Roel Kuijer; Els Terwindt‐Rouwenhorst; Ton van der Linden; Sjoerd Bulstra
- Publisher
- Elsevier Science; Wiley (John Wiley & Sons); Wiley-Blackwell; Wiley (ISSN 0736-0266)
- Published
- 1999
- Language
- EN
- Field
- Medicine (Health Sciences)