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What is Metallothionein-I/II in Neuroprotection about?
This document discusses the role of metallothionein-I/II (MT-I/II) in neuroprotection. It states that MT-I/II expression is induced in the central nervous system in response to various pathogens and disorders, mainly in reactive glial cells. MT-I/II help reduce inflammation, oxidative stress, neurodegeneration and apoptosis, while promoting repair, regeneration, angiogenesis and neurogenesis. Intracellularly, MT-I/II act by controlling metal ions and reactive oxygen species. Extracellularly, MT-I/II signal
- Author
- Eman Shaltout
- Language
- EN