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Effect of the interval between birth and second dose of hepatitis B vaccine on perinatal transmission of hepatitis B virus by Tae Un Yang; Juan C. Vargas-Zambrano; Hang A Park; Chae Won Jung; Dongwook Kim; Youngmee Jee is a Medicine article available to read on EtoBox.
What is Effect of the interval between birth and second dose of hepatitis B vaccine on perinatal transmission of hepatitis B virus about?
## ABSTRACT Preventing perinatal transmission is important for hepatitis B (HepB) elimination. We conducted a retrospective cohort study to assess the interval between HepB birth-dose (HepB-BD) to second-dose (HepB-SD) vaccination on perinatal transmission. Among 39,313 infants born to HepB s-antigen (HBsAg)-positive mothers from a Korean national database 38,411 (97.7%) had completed timely immunophylaxis with HepB-BD 41,572 (99.8%) with hepatitis B immune globulin, and 1027 (2.6%) were HBsAg-positive at ≥ 9 months. Maternal factors (i.e. HepB e-antigen status, age, or nationality) were associated with an increased risk of infection whereas short gestational length decreased it. The HepB-BD – HepB-SD interval (<8 vs. ≥8 weeks) did not alter the risk.
Who reads Effect of the interval between birth and second dose of hepatitis B vaccine on perinatal transmission of hepatitis B virus?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Tae Un Yang; Juan C. Vargas-Zambrano; Hang A Park; Chae Won Jung; Dongwook Kim; Youngmee Jee
- Publisher
- Taylor & Francis
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)