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Quantification of myocardial perfusion using CMR with a radial data acquisition: comparison with a dual-bolus method by Tae Ho Kim; Nathan A Pack; Liyong Chen; Edward VR DiBella is a Medicine article available to read on EtoBox.

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## Abstract ## Background Quantitative estimates of myocardial perfusion generally require accurate measurement of the arterial input function (AIF). The saturation of signal intensity in the blood that occurs with most doses of contrast agent makes obtaining an accurate AIF challenging. This work seeks to evaluate the performance of a method that uses a radial k-space perfusion sequence and multiple saturation recovery times (SRT) to quantify myocardial perfusion with cardiovascular magnetic resonance (CMR). ## Methods Perfusion CMR was performed at 3 Tesla with a saturation recovery radial turboFLASH sequence with 72 rays. Fourteen subjects were given a low dose (0.004 mmol/kg) of dilute (1/5 concentration) contrast agent (Gd-BOPTA) and then a higher non-dilute dose of the same volume (0.02 mmol/kg). AIFs were calculated from the blood signal in three sub-images with differing effective saturation recovery times. The full and sub-images were reconstructed iteratively with a total variation constraint. The images from the full 72 ray data were processed to obtain six tissue enhancement curves in two slices of the left ventricle in each subject. A 2-compartment model was used to de

Who reads Quantification of myocardial perfusion using CMR with a radial data acquisition: comparison with a dual-bolus method?

Author

Tae Ho Kim; Nathan A Pack; Liyong Chen; Edward VR DiBella

Publisher

BioMed Central; Springer (Biomed Central Ltd.); New York NY: Marcel Dekker; New York N.Y.: Informa Healthcare; London: 2008-; Informa UK Limited; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1097-6647)

Published

2010

Language

EN

Field

Medicine (Health Sciences)