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Synthesis of Fluorescent Artificial Receptors with High Specificity for Simultaneous Detection of Non-steroidal Anti-inflammatory Drugs by Tingting Wang; Qianjin Li; Meng Wang; Jianhong Xu; Jianlin Li; Fenying Wang is a Agricultural and Biological Sciences article available to read on EtoBox.

What is Synthesis of Fluorescent Artificial Receptors with High Specificity for Simultaneous Detection of Non-steroidal Anti-inflammatory Drugs about?

Development of multiple detection methods to monitor non-steroidal anti-inflammatory drugs (NSAIDs) in food is an effective way to protect human health. Here, we aimed to synthesize fluorescent artificial receptors by molecular imprinting technique to construct a simultaneous detection system targeting NSAIDs. Rhodamine B and fluorescein-functionalized silanes were employed as the fluorescence signal reporters for naproxen and ketoprofen, respectively. Two fluorescent molecularly imprinted polymers (FMIPs) were obtained with high specificity, giving cross-reactivity factors of 6.4–15.8 (naproxen) and 2.6–25.6 (ketoprofen). Both FMIPs also displayed rapid response time (5 min) and high sensitivity (detection limit at ∼ nM level). A simultaneous detection system was constructed based on the FMIPs and applied for sensing the spiked NSAIDs in real samples, showing recoveries of 71–119 %, comparable with the HPLC methods (70–113 %). In summary, use of different FMIPs to construct simultaneous detection systems is practicable, and provides a flexible way for sensing multiple hazards in food samples.

Who reads Synthesis of Fluorescent Artificial Receptors with High Specificity for Simultaneous Detection of Non-steroidal Anti-inflammatory Drugs?

It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.

Author
Tingting Wang; Qianjin Li; Meng Wang; Jianhong Xu; Jianlin Li; Fenying Wang
Publisher
Elsevier BV
Published
2023
Language
EN
Field
Agricultural and Biological Sciences (Life Sciences)