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The document introduces a novel rodent model of menopause called Accelerated Ovarian Failure (AOF), which effectively replicates human perimenopause and postmenopause, addressing limitations of existing models. The AOF model utilizes the chemical 4-vinylcyclohexene diepoxide (VCD) to induce ovarian failure while preserving ovarian tissue, allowing for the study of hormone effects independent of aging. This model aims to enhance understanding of women

Author

fudllatsuroyyaa

Language

EN