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Can I read Evaluation of High-Pressure Processing in Inactivation of the Hepatitis E Virus on EtoBox?
Evaluation of High-Pressure Processing in Inactivation of the Hepatitis E Virus by Nasheri, Neda ;Doctor, Tanushka ;Chen, Angela ;Harlow, Jennifer ;Gill, Alexander is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Evaluation of High-Pressure Processing in Inactivation of the Hepatitis E Virus about?
Hepatitis E virus (HEV) causes acute hepatitis with approximately 20 million cases per year globally. Based on genetic diversity, HEV is classified into different genotypes, with genotype 3 (HEV-3) being most prevalent in Europe and North America. The transmission of HEV-3 has been shown to be zoonotic and mainly associated with the consumption of raw or undercooked pork products. Herein, we investigated the efficacy of high-pressure processing (HPP) in inactivation of HEV-3 using a cell culture system. HPP has been indicated as a promising non-thermal pathogen inactivation strategy for treatment of certain high-risk food commodities, without any noticeable changes in their nature. For this purpose, we treated HEV-3 in media with different conditions of HPP: 400 MPa for 1 and 5 min, as well as 600 MPa for 1 and 5 min, at ambient temperature. All four HPP treatments of HEV in media were observed to result in a 2-log reduction in HEV load, as determined by the amounts of extracellular HEV RNA produced at 14-day post-infection, using the A549/D3 cell culture system. However, application of the same treatments to artificially contaminated pork pâté resulted in 0.5 log reduction in vira
Who reads Evaluation of High-Pressure Processing in Inactivation of the Hepatitis E Virus?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Nasheri, Neda ;Doctor, Tanushka ;Chen, Angela ;Harlow, Jennifer ;Gill, Alexander
- Publisher
- Frontiers; Frontiers Media SA; Frontiers Media S.A.; Lausanne: Frontiers Media S.A., 2010-; Publons (ISSN 1664-302X)
- Published
- 2020
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)