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Testicular Germ Cell Tumors in Patients with Human Immunodeficiency Virus Infection by Marcus U. Hentrich; Norbert G. Brack; Peter Schmid; Tobias Schuster; Christoph Clemm; Reiner C. Hartenstein is a Medicine article available to read on EtoBox.

What is Testicular Germ Cell Tumors in Patients with Human Immunodeficiency Virus Infection about?

## BACKGROUND. There has been evidence of a higher incidence of testicular germ cell tumors (GCT) in human immunodeficiency virus (HlV)-seropositive men than in the non HIV-infected male population. Most authors recommend standard therapy for HIV-positive patients with GCT but the immunosuppressive effects of Chemotherapy and/or radiotherapy must be considered. ## METHODS. The records of all patients in whom testicular cancer was diagnosed andlor treated at a single institution between January 1986 and July 1995 were reviewed with regard to HIV seropositivity. Tumor histology, initial staging, treatment, and the patients' outcomes were analyzed in connection with a review of the literature. RESULTS. Six patients with GCT and documented HIV seropositivity at the time of tumor diagnosis (four homosexuals, one bisexual, and one heterosexual former intravenous drug abuser) of 192 documented cases of testicular cancer are reported. In addition, 1 patient proved to be HIV seropositive 34 months after completing chemotherapy (vinblastine, ifosfamide, and cisplatin) for Stage IIB (minimal disease) seminoma. Intensified platinum-based chemotherapy was administered to two patients with clini

Who reads Testicular Germ Cell Tumors in Patients with Human Immunodeficiency Virus Infection?

Author

Marcus U. Hentrich; Norbert G. Brack; Peter Schmid; Tobias Schuster; Christoph Clemm; Reiner C. Hartenstein

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

1996

Language

EN

Field

Medicine (Health Sciences)