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Risk factors for isolated biliary atresia, National Birth Defects Prevention Study, 1997–2002 by Natalie S. The; Margaret A. Honein; Alissa R. Caton; Cynthia A. Moore; Anna Maria Siega-Riz; Charlotte M. Druschel is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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## Abstract Biliary atresia is a rare birth defect that affects 1 in 12,000 to 1 in 19,500 live births. We used data from the National Birth Defects Prevention Study, a multistate case‐control study, to identify potential risk factors for isolated biliary atresia (no additional unrelated major birth defects diagnosed). Infants were identified from eight states from 1997 to 2002, with clinical information abstracted from medical records. Potential risk factors assessed include: demographic factors, seasonality, preterm birth, maternal smoking, maternal alcohol use, maternal illicit drug use, maternal health, maternal medication use, maternal vitamin use, and maternal nutrition. Infants of non‐Hispanic black mothers were more likely to have biliary atresia than infants of non‐Hispanic white mothers (adjusted odds ratio (aOR) = 2.29, 95% confidence interval (CI) 1.07–4.93) and infants conceived during the spring season were more likely to have biliary atresia than infants conceived in winter (aOR = 2.33, 95%CI 1.05–5.16). Low intakes of vitamin E, copper, phosphorus, and beta tocopherol were associated with the occurrence of isolated biliary atresia (borderline significance). Low iron

Who reads Risk factors for isolated biliary atresia, National Birth Defects Prevention Study, 1997–2002?

Author

Natalie S. The; Margaret A. Honein; Alissa R. Caton; Cynthia A. Moore; Anna Maria Siega-Riz; Charlotte M. Druschel

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); Wiley-Liss Inc; Wiley (ISSN 1552-4825)

Published

2007

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)