Can I read Simultaneous Determination of Residual Stilbenes and Stilbene Metabolites in Animal Tissue by Liquid Chromatography–tandem Mass Spectrometry on EtoBox?

Simultaneous Determination of Residual Stilbenes and Stilbene Metabolites in Animal Tissue by Liquid Chromatography–tandem Mass Spectrometry by Xu Hong; Gu Long; He jia; Lin Anqing; Tang Danzhou is a Chemistry article available to read on EtoBox.

What is Simultaneous Determination of Residual Stilbenes and Stilbene Metabolites in Animal Tissue by Liquid Chromatography–tandem Mass Spectrometry about?

A liquid chromatographic (LC)-tandem mass spectrometry (MS/MS) method was developed for simultaneous determination of stilbenes, diethylstilbestrol (DES), hexestrol (HEX), and dienoestrol (DEN) in animal tissue. Sample clean-up and analyte enrichment was performed by automated solid-phase extraction (ASPE) with a silica gel cartridge. Detection capabilities (CC␤) related to the transition products of lowest abundance for the method were 0.04-0.45 ng g -1 in tissue and were achieved using atmospheric pressure chemical ionization (APCI) in negative mode. The use of an internal standard in combination with the simplified sample preparation led to a sensitive and reliable analytical method. The recovery level of the method was 84-108% for DES and DEN between 0.5 and 5 ng g -1 , and 59-87% for HEX between 0.25 and 2.5 ng g -1 .

Who reads Simultaneous Determination of Residual Stilbenes and Stilbene Metabolites in Animal Tissue by Liquid Chromatography–tandem Mass Spectrometry?

Author

Xu Hong; Gu Long; He jia; Lin Anqing; Tang Danzhou

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1873-376X)

Published

2007

Language

EN

Field

Chemistry (Physical Sciences)