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In Situ Synthesis and Cell Line Studies of Nano-hydroxyapatite/graphene Oxide Composite Materials for Bone Support Applications by Melike Nur Ozder; Fatih Ciftci; Ozge Rencuzogullari; Elif Damla Arisan; Cem Bülent Ustündag is a Materials Science article available to read on EtoBox.
What is In Situ Synthesis and Cell Line Studies of Nano-hydroxyapatite/graphene Oxide Composite Materials for Bone Support Applications about?
The current work presents and discusses the findings of on the structural, chemical and thermal properties of in situ synthesis of graphene oxide-hydroxyapatite (GO/HA) nanocomposite materials doped with graphene oxide (w/w) at different ratios of 0%, 0.1%, 0.5% and 1% for bone tissue support applications. Microstructure and crystallinity were investigated by Fourier transform infrared spectroscopy (FT-IR), Raman spectroscopy, X-ray diffraction (XRD), thermogravimetric analysis (TGA), pore structures by Brunauner-Emmett-Teller (BET) analysis, Dynamic light scattering (DLS). Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) were performed to characterize the morphology of the bone support scaffold materials. The attachment and cell viability of fibroblast NIH/3T3 cells were observed on the synthesized bone support composite materials. Excellent proliferation of bone support scaffolds containing 0.5% and 1% GO (w/w) was observed by fluorescence microscopy using 3,3′-Dihexyloxacarbocyanine iodide (Dio-6), 4′,6-diamidino-2-phenylindole (DAPI), MitoRed and Anti-Vinculin. The innovative materials revealed in this study demonstrated that GO and HA promoted cell
Who reads In Situ Synthesis and Cell Line Studies of Nano-hydroxyapatite/graphene Oxide Composite Materials for Bone Support Applications?
It is typically read by researchers, students, and practitioners in Materials Science.
- Author
- Melike Nur Ozder; Fatih Ciftci; Ozge Rencuzogullari; Elif Damla Arisan; Cem Bülent Ustündag
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Materials Science (Physical Sciences)