Can I read Mobile Phase Effects in Reversed-phase Chromatography on EtoBox?

Mobile Phase Effects in Reversed-phase Chromatography by Wayne R. Melander; Bor-Kuan Chen; Csaba Horvàth is a Chemistry article available to read on EtoBox.

What is Mobile Phase Effects in Reversed-phase Chromatography about?

Enthalpy+ntropy compensation observed in reversed-phase chromatography affords an expression of ffie free energy change associated with the chromatographic process as a function of both the eiuent composition and temperature. It takes a simple form and reveals the existence of a noncompensating enthalpy residue in the absence of heat capacity e&&s when the free energy change is linear in solvent composition. Statistical analysis confirmed that the resulting three-parameter equation sufXks to transform retention data for a solute obtained at a given temperature and solvent composition to another set of experimental conditions. With arylalkanes investigated so far, the parameters exhibit 3 linear relationship with the carbon number of the solutes. These findings suggest the possibility of cons&u&g a hydrophobic index system for characterization of biological substances on the basis of retention data. INTRODUCT'ION During the short history of reversed-phase chromatography (RFC) with hydrocarbonaceous bonded phases a great deal of evidence has accumulated that by using aqueous methanol or acetonitrile as the eluent. the free energy for the chromatographic process is linear in the solve

Who reads Mobile Phase Effects in Reversed-phase Chromatography?

Author

Wayne R. Melander; Bor-Kuan Chen; Csaba Horvàth

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1873-3778)

Published

1979

Language

EN

Field

Chemistry (Physical Sciences)