Can I read The Risk of Pancreatic Cancer in Patients with Gastric or Duodenal Ulcer Disease on EtoBox?

The Risk of Pancreatic Cancer in Patients with Gastric or Duodenal Ulcer Disease by Juhua Luo; Caroline Nordenvall; Olof Nyrén; Hans‐Olov Adami; Johan Permert; Weimin Ye is a Medicine article available to read on EtoBox.

What is The Risk of Pancreatic Cancer in Patients with Gastric or Duodenal Ulcer Disease about?

## Abstract Although __Helicobacter pylori__ (__H. pylori__) seropositivity is linked to an excess risk of pancreatic cancer, the biologic mechanism is unknown. Gastric ulcer is primarily associated with corpus colonization of __H. pylori__, atrophic gastritis and formation of __N__‐nitrosamines. Duodenal ulcer is a marker of antral colonization, hyperacidity and uninhibited secretin release. We estimated relative risks for pancreatic cancer among patients with gastric or duodenal ulcer, based on a register‐based retrospective cohort study with 88,338 patients hospitalized for gastric ulcer and 70,516 patients for duodenal ulcer recorded in the Swedish Inpatient Register between 1965 and 2003. Following operation, the 14,887 patients who underwent gastric resection and 8,205 with vagotomy were analyzed separately. Multiple record‐linkages allowed complete follow‐up and identification of all incident cases of pancreatic cancer until December 31, 2003. Standardized incidence ratios (SIRs) estimated relative risks. During years 3–38 of follow‐up, we observed a 20% excess risk (95% confidence interval [CI] 10–40%) for pancreatic cancer among unoperated gastric ulcer patients. The exces

Who reads The Risk of Pancreatic Cancer in Patients with Gastric or Duodenal Ulcer Disease?

Author

Juhua Luo; Caroline Nordenvall; Olof Nyrén; Hans‐Olov Adami; Johan Permert; Weimin Ye

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)

Published

2006

Language

EN

Field

Medicine (Health Sciences)