Opening book details…
Can I read The Challenge and Opportunity of NTRK Inhibitors in Non-Small Cell Lung Cancer on EtoBox?
The Challenge and Opportunity of NTRK Inhibitors in Non-Small Cell Lung Cancer by Haixia Qin; Manish Patel is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is The Challenge and Opportunity of NTRK Inhibitors in Non-Small Cell Lung Cancer about?
With the development of targeted therapy, non-small cell lung cancer (NSCLC) patients could have more treatment choices if target mutation presents. The neurotrophic tropomyosin receptor kinase (NTRK) has a low prevalence in NSCLC, roughly around 0.5%. FDA had approved two first generation NTRK inhibitors, larotrectinib and entrectinib. Both medications have excellent CNS penetration. This manuscript will review available data on targeting NTRK fusions in NSCLC and mechanisms of drug resistance.
Who reads The Challenge and Opportunity of NTRK Inhibitors in Non-Small Cell Lung Cancer?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Haixia Qin; Manish Patel
- Publisher
- MDPI AG
- Published
- 2022
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)