Opening book details…
Can I read Cohesive Cancer Invasion of the Biophysical Barrier of Smooth Muscle on EtoBox?
Cohesive Cancer Invasion of the Biophysical Barrier of Smooth Muscle by William L. Harryman; Kendra D. Marr; Daniel Hernandez-Cortes; Raymond B. Nagle; Joe G. N. Garcia; Anne E. Cress is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Cohesive Cancer Invasion of the Biophysical Barrier of Smooth Muscle about?
Smooth muscle is found around organs in the digestive, respiratory, and reproductive tracts. Cancers arising in the bladder, prostate, stomach, colon, and other sites progress from low-risk disease to high-risk, lethal metastatic disease characterized by tumor invasion into, within, and through the biophysical barrier of smooth muscle. We consider here the unique biophysical properties of smooth muscle and how cohesive clusters of tumor use mechanosensing cell-cell and cell-ECM (extracellular matrix) adhesion receptors to move through a structured muscle and withstand the biophysical forces to reach distant sites. Understanding integrated mechanosensing features within tumor cluster and smooth muscle and potential triggers within adjacent adipose tissue, such as the unique damage-associated molecular pattern protein (DAMP), eNAMPT (extracellular nicotinamide phosphoribosyltransferase), or visfatin, offers an opportunity to prevent the first steps of invasion and metastasis through the structured muscle.
Who reads Cohesive Cancer Invasion of the Biophysical Barrier of Smooth Muscle?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- William L. Harryman; Kendra D. Marr; Daniel Hernandez-Cortes; Raymond B. Nagle; Joe G. N. Garcia; Anne E. Cress
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)