Opening book details…
Can I read Assessment of Exposure to Pesticides: Residues in 24 H Duplicate Diets Versus Their Metabolites in 24 H Urine Using Suspect Screening and Target Analysis on EtoBox?
Assessment of Exposure to Pesticides: Residues in 24 H Duplicate Diets Versus Their Metabolites in 24 H Urine Using Suspect Screening and Target Analysis by R. Nijssen; A. Lommen; H. van den Top; R. van Dam; C. Meuleman-Bot; M. Tienstra; P. Zomer; S. Sunarto; F. van Tricht; M. Blokland; H. Mol is a Chemistry article available to read on EtoBox.
What is Assessment of Exposure to Pesticides: Residues in 24 H Duplicate Diets Versus Their Metabolites in 24 H Urine Using Suspect Screening and Target Analysis about?
Human biomonitoring can add value to chemical risk assessment by reducing the assumptions regarding consumption rates, residue occurrence, and processing effects and by integrating exposures from different sources (diet, household use, environmental). However, the relationship between exposure and concentration in human matrices is unknown for most pesticides. Therefore, we conducted a pilot study to gain more insight into the qualitative and quantitative relationship between dietary intake of pesticides (external exposure) and urinary excretion (reflecting internal exposure). In this cross-sectional observational study, 35 healthy consumers aged 18–65 years from the region of Wageningen, Netherlands, collected an exact duplicate portion of their diets during 24 h. On the same day, they also collected all their urine. The duplicate diets were analyzed using target screening by GC- and LC-HRMS; each duplicate diet contained at least five, up to 21, pesticide residues. The 24 h urine samples were analyzed using LC-HRMS in a suspect screening workflow. Metabolites were tentatively detected in all 24 h urine samples, ranging from six metabolites corresponding to four pesticides up to 4
Who reads Assessment of Exposure to Pesticides: Residues in 24 H Duplicate Diets Versus Their Metabolites in 24 H Urine Using Suspect Screening and Target Analysis?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- R. Nijssen; A. Lommen; H. van den Top; R. van Dam; C. Meuleman-Bot; M. Tienstra; P. Zomer; S. Sunarto; F. van Tricht; M. Blokland; H. Mol
- Publisher
- Springer
- Published
- 2023
- Language
- EN
- Field
- Chemistry (Physical Sciences)